High levels of DNA damage in nerve cells can lead to dementia
Scientists from the world-leading Sheffield Institute for Translational Neuroscience (SITraN) have discovered a novel pathway contributing to dementia in individuals that lack the typical signs of...
View ArticleDNA damage seen in patients undergoing CT scanning, study finds
Using new laboratory technology, scientists have shown that cellular damage is detectable in patients after CT scanning, according to a new study led by researchers at the Stanford University School of...
View ArticleNew 'chemotherapy booster' could treat lung and pancreatic cancer
A new drug that blocks cancer's escape route from chemotherapy could be used to treat deadly lung and pancreatic cancers, research has revealed.
View ArticleStrange circular DNA may offer new way to detect cancers
Strange rings of DNA that exist outside chromosomes are distinct to the cell types that mistakenly produced them, researchers have discovered. The finding raises the tantalizing possibility that the...
View ArticleStress responder is a first responder in helping repair DNA damage and...
DNA damage increases the risk of cancer, and researchers have found that a protein, known to rally when cells get stressed, plays a critical, early step in its repair.
View ArticleNew research helps explain why a deadly blood cancer often affects children...
In equatorial Africa, a region of the globe known as the "lymphoma belt," children are ten times more likely than in other parts of the world to develop Burkitt's lymphoma, a highly aggressive blood...
View ArticleThree earn prestigious awards for studies of cancer, DNA damage
Three researchers won prestigious medical awards Tuesday for a new approach to treating cancer and insights into how creatures deal with DNA damage.
View ArticleProtein NBS1 is crucial for macrophage functional activity
Protein NBS1, which plays a key role in DNA damage repair, is required for macrophage functional activity. This is one of the conclusions of a scientific paper published in the journal Blood by a team...
View ArticleTreating cancer by exploiting how its DNA is repaired
In every cell in your body, DNA is constantly getting damaged.
View ArticleScientists establish model of Hutchinson-Gilford Progeria Syndrome
Scientists from A*STAR's Institute of Medical Biology (IMB) have successfully established a comprehensive model of rare accelerated ageing syndrome Hutchinson-Gilford Progeria Syndrome (HGPS), thereby...
View ArticleResearchers conduct high-res analyses on lesions in tissue
A precise understanding of how ion beams affect biological tissue is of great importance for both radiotherapy applications and the assessment of radioprotection risks, e.g. to astronauts on long term...
View ArticleChemistry nobel DNA research lays foundation for new ways to fight cancer
Our cells are up against a daily onslaught of damage to the DNA that encodes our genes. It takes constant effort to keep up with the DNA disrepair – and if our cells didn't bother to try to fix it, we...
View ArticlePreclinical study shows potential to increase the effectiveness of leukemia...
Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 (CHD4) may...
View ArticleGenomic fingerprint can highlight which breast, ovarian, pancreatic and...
Gastric cancer, otherwise known as stomach cancer, does not respond well to existing treatments and it is currently the third leading cause of cancer death in the world (after lung and liver cancer)....
View ArticleScientists identify 'checkpoint' to prevent birth defects and spontaneous...
Researchers from the University of Southampton have established that eggs have a protective 'checkpoint' that helps to prevent DNA damaged eggs being fertilised.
View ArticleImproper diet linked to future health complications
A Telethon Kids Institute-led study has found low levels of plasma calcium, vitamin E (alpha-tocopherol) and lutein—micronutrients found in foods like spinach and eggs—to be associated with DNA damage...
View ArticleChemist talks HPV, antivirals, progress toward cure
Human papillomavirus is the most common sexually transmitted infection in the U.S. according to the Centers for Disease Control and Prevention. That fact alone makes the work of James Bashkin, a...
View ArticleDNA repair protein BRCA1 implicated in cognitive function and dementia
Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer's disease.
View ArticleRecurrent aphthous stomatitis linked to oxidative stress
(HealthDay)—Recurrent aphthous stomatitis is associated with increased total oxidative status and oxidative stress index values, according to a study published online Dec. 1 in the International...
View ArticleBone drug protects stem cells from ageing
Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.
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